Vital information for discovering and optimizing new drugs "Understanding the data and the experimental details that support it has always been at the heart of good science and the assumption challenging process that leads from good science to drug discovery. This book helps medicinal chemists and pharmacologists to do exactly that in the realm of enzyme inhibitors." -Paul S. Anderson, PhD This publication provides readers with a thorough understanding of enzyme-inhibitor evaluation to assist them in their efforts to discover and optimize novel drug therapies. Key topics such as competitive, noncompetitive, and uncompetitive inhibition, slow binding, tight binding, and the use of Hill coefficients to study reaction stoichiometry are all presented. Examples of key concepts are presented with an emphasis on clinical relevance and practical applications. Targeted to medicinal chemists and pharmacologists, Evaluation of Enzyme Inhibitors in Drug Discovery focuses on the questions that they

Neuroscience has dramatically increased understanding of how mental states and processes are realized by the brain, thus opening doors for treating the multitude of ways in which minds become dysfunctional. This book explores questions such as when is it permissible to alter a person's memories, influence personality traits or read minds? What can neuroscience tell us about free will, self-control, self-deception and the foundations of morality? The view of neuroethics offered here argues that many of our new powers to read ,alter and control minds are not entirely unparalleled with older ones. They have, however, expanded to include almost all our social, political and ethical decisions. Written primarily for graduate students, this book will appeal to anyone with an interest in the more philosophical and ethical aspects of the neurosciences.

Emergency Medicine Handbook: Critical Concepts for Clinical Practice provides essential information and practical advice for use in the emergency department. The book covers the general approach to patients with various medical complaints, tables of differential diagnoses, and brief discussions of the most common disease processesall in an easy-to-read, bulleted format. Essential information for use in the busy ED. Templated chapters written in bulleted format makes finding information fast and easy! Includes algorithms and text boxes that help you comprehend information faster.

Now part of the popular LPN Threads series, the new full-color edition of this market-leading textbook presents a clear, well-organized exploration of pediatric nursing for LPN/LVN students. It integrates cutting edge information with updated content, offering useful learning tools to reinforce fundamental concepts. Organized according to developmental stages, the book covers pediatric nursing from infancy to adolescence, with a separate chapter on end-of-life care for children and their families. With its easy-to-read, clear writing style, it provides exactly the right depth and breadth of content for LPN/LVNs. Skills teach basic techniques performed by the LPN/LVN in pediatric nursing settings. Healthy People 2010 objectives are incorporated throughout the text to familiarize readers with these key federal guidelines and objectives. Nursing Care Plans follow the nursing process format, with critical thinking question at the end. Nursing Briefs stress important content-related p

From 'Abcissa' to 'Zygosity determination' - this accessible introduction to the terminology of medical statistics describes more than 1500 terms all clearly explained, illustrated and defined in non-technical language, without any mathematical formulae! With the majority of terms revised and updated and the addition of more than 100 brand new definitions, this new edition will enable medical students to quickly grasp the meaning of any of the statistical terms they encounter when reading the medical literature. Furthermore, annotated comments are used judiciously to warn the unwary of some of the common pitfalls that accompany some cherished biomedical statistical techniques. Wherever possible, the definitions are supplemented with a reference to further reading where the reader may gain a deeper insight, so whilst the definitions are easily disgestible, they also provide a stepping stone to a more sophisticated comprehension. Statistical terminology can be quite bewildering for clinicians: this guide will b

Medical Physiology is a new, full-color, comprehensive textbook designed for modern medical school courses in human physiology. The most up-to-date and beautifully illustrated text on the market, it has a strong molecular and cellular approach, firmly relating the molecular and cellular biological underpinnings of physiology to the study of human physiology and disease. Contributions from leading physiologists ensure authoritative, cutting-edge information, and thorough and consistent editing have produced a readable and student-friendly text.

MANUAL OF HIGH RISK PREGNANCY AND DELIVERY, 2ND EDITION provides the practicing perinatal nurse in obstetric facilities with comprehensive in one accessible text. The text covers the must-knows of care screening for risk factors, providing preventive management, and intervening appropriately when problems arise. Various problems are presented in a consistent format that includes incidence, etiology, physiology, pathophysiology, and medical management with protocols for nurse practitioners. Collaborative problems and desired outcomes are also addressed. The book also discusses the role of the advance practice nurse implementing care. This completely revised edition includes. current AWHONN Standards of Practice and NANDA nursing diagnoses, a new chapter on complementary and alternative therapies, new content on multiple gestation including nutritional needs and preterm management, and new information on domestic violence, thrombophilias and other connective tissue disorders.

Pharmacists are required to make certain kinds of calculations that determine the quantities of materials required for filling pre*ions and making up formulas. The new and expanded topics introduced in the fourth edition teach pharmacists and pharmacy students how to do the calculations required in current practice, covering important areas such as handling injectibles, including those used in parenteral nutrition and radiopharmaceuticals. The book also includes new chapters on isotonicity, intravenous fluids, and nutritional calculations. Features: New concepts introduced in sequence, encouraging the student to master each concept before moving ahead Many examples and practice problems, all with answers and the availability of rapid feedback build confidence Filled with practical instruction relevant to the problems pharmacist face in their practice

Ophthalmology at a Glance is a concise textbook written as part of the highly successful at a Glance series. The book follows the classic format of topics laid out in a double page spread, with clear diagrams illustrating the essential information and supporting the main text. This makes learning and understanding a topic more simple and effective. Ophthalmology at a Glance is written to provide a straightforward and easy-to-use guide for the Ophthalmology course. The introductory section includes an overview of the subject and it's sub-specialities, an outline of what exact knowledge and skills medical students and junior doctors need to acquire, and covers the social and occupational aspects of vision. A guide to History and Examination techniques is followed by the key detail on common problems and diseases. The book is divided into 13 sections covering: Principles of ophthalmology Ophthalmic History and Examination Correction of refractive errors Basic eye examination Acute ophthalmology Gr

This is a very well designed review book covering all areas of clinical microbiology that capitalizes on the need of trainees to refresh knowledge prior to taking standardized examinations.

...a portable paperback reference, providing "how-to" guidance, step-by-step instructions for every diagnostic and therapeutic procedure in adult critical care, and graphic illustrations.

The only atlas devoted to the physical diagnosis of pain! Dr. Steven Waldman presents a clear, how-to-do-it approach to the accurate diagnosis of 300 conditions through their physical signs and symptoms. Six hundred illustrations and a bonus DVD with video-clips make every technique easy to understand and apply. Examines the full range of conditions in the shoulder and upper extremity, elbow and forearm, wrist and hand, spine, hip, knee, ankle, and foot. Integrates 100 original color drawings by respected medical illustrator Joe Bloch as well as 500 crisply reproduced radiographic and MR images. Demonstrates how to perform physical examinations for pain with videoclips on DVD of Dr. Waldman and his staff evaluating patients.

This is not a book on how to make a diagnosis, but rather starts from the point of diagnosis and covers all the main neurological conditions as such as stroke, Parkinson's disease, epilepsy and migraine well as some of the rarer conditions such as Wilson's disease showing which treatments are evidence-based but also describing those which at present need more trials. Each condition is described in the following way: definition, cause, frequency, and prognosis. Written by expert contributors, this book describes the treatment that neurologists are responsible for, indicates when to refer, shows complications of treatment, as well as drug interactions. ·A quick-reference pocket guide ·Evidence-based treatment described ·Adverse effects of treatment mentioned along with their likelihood ·Advice given on when to refer ·Drug treatments interactions, costs, dosages are covered extensively

Psychiatry at a Glance provides a concise and visually—orientated summary of core psychiatric knowledge． It is aimed primarily at clinical undergraduate medical students undertaking their psychiatry attachment and revising for final examinations．The tables and diagrams encapsulate all a student needs to know in order to pass．whilst the text supplies the extra detail necessary to do well． It is equally useful to those training in allied health professions such as nursing，social work，psychology and pharmacy，and to psychiatric trainees，all of whom will find in it a clear and user—friendly overview of psychiatry． This edition has been thoroughly updated and a new chapter on psychiatric emergencies has been added．Key references for each chapter are provided，and readers can assess their progress by using the multiple choice questions at the end of the book．

The new edition of this popular handbook features 545 illustrations，new ＆thoroughly updated imaging protocols，bulleted key facts on technique and differential diagnosis，a new chapter on degenerative brain disorders， and more。 Univ。of North Carolina， Chapel Hill。Selection for neuroradiology residents and clinicians。Presents images of all common neurologic diseases and key facts about techniques and differential diagnosis。Previous edition：c1995。Halftone illustrations。Softcover。DNLM： Central Nervous System Diseases--radiography handbooks。

Completely revised and updated, this reference of choice for students and practitioners offers practical guidance and the latest information on normal growth and development, along with the diagnosis, management, and prevention of common childhood diseases and disorders. Discussions of the pathophysiologic aspects of pediatric disease, the genetic bases of disease, and the psychosocial dynamics of illness aid in the clinical decision-making process. What's more, the New Edition is streamlined for more focused, consistent coverage of core areas of pediatrics and also includes STUDENT CONSULT access, which allows users to integrate additional vital information. Focuses on the core aspects of pediatric health and disease. Emphasizes the pathophysiologic aspects of pediatric disease and the psychosocial dynamics of illness. Covers the genetic bases of disease, when applicable, since the understanding is critical for clinical decision making. Uses summary tables that enable quick review.

Review/USMLE/Pharmacology REAL-LIFE CLINICAL CASES for the Basic Sciences and USMLE Step 1 Clinical correlations are increasingly emphasized in the teaching of basic medical science. Students, therefore, need exposure to clinical cases to pass course exams and ace the USMLE Step 1. This book presents 52 real-life clinical cases illustrating essential concepts in pharmacology. Each case includes an easy-to-understand discussion correlated to key basic science concepts, definitions of key terms, pharmacology pearls, and USMLE-style review questions. This interactive learning system helps you to learn instead of memorize. 52 clinical cases correlated to high-yield pharmacology concepts Pharmacology Pearls highlight key points USMLE-style comprehension questions with each case Primer on how to approach the basic sciences Proven learning system improves exam scores Visit us at www.accessmedbooks.com McGraw-Hill Professional LANGE

QBase Anaesthesia 3 is the third volume in the QBase series of book + CD-ROM packages and is aimed at the FRCA candidate. Both the book and CD contain 555 questions divided into a number of pre-set exams (with accompanying fully referenced explanatory notes) and there are also a number of pre-set short exams to attempt, utilising the questions in the book. The CD-ROM can be installed in seconds and gives the reader an incredible range of options, greatly increasing the utility and value of the book. Not only can the reader practice the set exams, but the program will mark these exams, allow the reader to customize exams to focus in on areas requiring further revision, shuffle the stems (A-E) to prevent the candidate from memorising 'patterns' and advise on examination strategy. It also has the facility to print out and store test results and provide helpful notes on each question. The CD-ROM accompanying this volume has been improved so that the exam analysis now gives a subject-based as well as an overall an

The Color Atlas of Domestic Violence is the first text to look specifically and comprehensively at the injuries frequently seen as a result of domestic violence. This atlas provides a visual aid for the examination, identification, and documentation of domestic injuries. It includes extensive visual content, as well as content on the cycles of violence and epidemiology of domestic violence. Specific injury types and patterns are both discussed and presented pictorially. The collection of needed forensic evidence is covered to help assure appropriate prosecution of the perpetrator. Psychological violence is included in addition to physical injury violence. This book can be read in its entirety to provide a strong background in domestic violence injuries or used as a spot reference to help understand when specific injuries may be the result of domestic violence. The primary focus is on adult females however, males, children, gays and lesbians, and older adults as victims are covered as well.

"This book is a Significant contribution to the medical literature...the information contained in this book has never before appeared in one place." -Fertility & Sterility,March 2004 Product De*ion This single, comprehensive guide details how virtually all of today's drugs and herbal supplements interact with pregnancy and lactation. Covering nearly 2,000 substances, it indicates precisely whether each one is FDA-approved for use by expecting or nursing mothers...is known to be safe for use...or is known to pose a danger.

This book presents radiological images covering the spectrum of radiology used in general surgery including plain X-rays, contrast studies, CT, MRI and nuclear medicine studies. Images in this text have been selected specifically to illustrate key features of importance in surgical diagnosis and management. Each section has been written in conjunction with a radiologist and practicing surgeon to ensure its clinical relevance. The text is divided into two main sections. The first focuses on the various forms of imaging ranging from plain film radiography up to PET scanning and nuclear medicine. The second section is organized by a series of clinical perspectives and illustrates the application of appropriate imaging techniques to clinical problems. Two section format covers both the radiological imaging techniques and the clinical perspectives. Highly cross-referenced between the two sections to ensure full coverage in both cases. Written by a contributor team of both surgeons and radio

Discover why admissions officers from the nation’s top medicalschools selected these essays of worthy applicants With only a limited number of spaces available every year to thethousands ofqualified applicants to the nation’s top medicalschools, a serious candidate must finda way to set himself orherself apart from the crowd. The essay is your one chancetohighlight the personal qualities and achievements that theapplication and MCATscores do not reveal. As Essays That Worked for Medical Schools demonstrates, there isno such thing asthe perfect submission. The winning essays cover awide range of interesting topics. If there is any similarity, it isthat they are written from the heart. One applicant writes abouthis work as a counselor for mentally ill adults and teens. Anothertells about the life-changing experience of delivering much neededsupplies to a leprosy village in West Africa. And a third applicanttalks about time spent volunteering at a local senior center. Fromthe thousands sub

Violence is all around us; yet, despite its widespread prevalence, we remain unclear about its causes. In this book Felicity de Zulueta - begins by defining "violence" as distinct from "aggression", and then attempts to trace its origins, highlighting the polarization between those who believe mankind to be innately violent and those who see violence as the outcome of man's life experiences. As a result of her investigations, the author suggests that the current high level of violence may well be linked to the effects of childhood and adult trauma which appear to be far more widespread than has hitherto been acknowledged. These findings are relevant to understanding why "normal" people can become violent in certain conditions. This is a second edition and has been fully updated. A new chapter on terrorism has been added.