FGF是一多基因家族，各成员之间具有一定的序列同源性和结构相似性。在人体许多组织内，具有广泛的生物学活性，参与一系列重要的生理和病理过程，具有临床治疗的潜在效果。本书共分九章，从FGF总论、FGF与受体及其结构与功能、FGF与疾病和FGF与生物工程等角度，系统整理了国内外有关FGF的*研究成果，阐述了FGF基础研究和应用方面的进展和成果。
This book assembles recent achievements in both basic research and clinical management in the field of hepatology, virology, and immunology. It provides up-to-date information for clinicians who can apply the relevant knowledge to their daily clinical practice and for researchers who are interested in clinically orientated studies. The updated and detailed technology and state-of-the-art treatment strategies provided in this book serve as references for clinicians and resident physicians in the daily management of ACLF. The rationality and strategies for basic research as well as patient management in this book can also be a valuable reference for other fatal and end-stage liver diseases than HBV-induced ACLF. This Volume 1 has six chapters and focuses on the definition, research technology, virology, genetics, and immunology. 本书汇集了在肝病、病毒学和免疫学领域的基础研究和临床领域的新成果。它为临床医师提供了新的信息，临床医师可以将相关知识应
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The principles and formulation of lipid-based drug delivery systems With its promise for improving drug absorption, the emerging field of lipid-based drug delivery systems has attracted considerable attention from academia to industry. Filling the need for a standard text on the subject, this book assembles a group of experienced investigators and educators from the front line of pharmaceutical sciences to provide a comprehensive resource on the fundamentals, formulation, and biopharmaceutical issues of lipid-based drug delivery. Presenting a solid grounding in the fundamental principles of lipid absorption in the intestines and vascular body systems, the text gives readers in-depth insight into the formulation issues, such as dissolution testing and stability testing, and physiological and biopharmaceutical issues, including the role of specific enzymes, the evaluation of transport systems in the body, and the mechanisms governing the transport of water-insoluble drugs. Chapters cover: ·Interac
the internal organization of the chapters is consistent...complemented with between one and nine clear illustrations per chapter." -- Neuroradiology "..this text is an excellent textbook of extracranial head and neck imaging that could benefit mxillofacial radiologist." -- Journal of Maxillofacial Radiology, April 2005 "This book proved hard to fault...pursues the topic to an authoritative depth and is highly recommended." -- The Journal of Otolaryngology of Otology, April 2005 Univ. of Michigan, Ann Arbor. Atlas provides a simplified approach to the complex anatomy and pathology of the head and neck. Presents CT and MR examples for more than 200 different diseases of the suprahyoid and infrahyoid neck, as well as clear and concise information on the epidemiology. clinical findings, pathology, and treatment guidelines. DNLM: Head--rediography.
This innovative new resource provides a highly visual introduction to the basic principles and practice of cardiology. Each topic is covered in a single two-page unit to make reference and study uncommonly easy and effective. Abundant full-color line diagrams, clinical photographs, and radiological images demonstrate essential concepts at a glance. An organization by both disease and symptom allows readers to approach any topic from either orientation. Concise, two-page units permit rapid review of a full range of scientific and clinical subjects. A wide selection of color clinical photographs, radiological images, ECGs, and other relevant illustrations present vital knowledge in a highly efficient, memorable manner. Attractive, well-designed page layouts display information in the most accessible manner possible. "Key Point" boxes facilitate study.
Breast cancer is the most common cancer among women in the Western world. Its incidence has gradually been rising and, since the introduction of screening mammography in the 1980s, its growth has even accelerated. Moreover, in some regions of Asia, a surge in incidence has also occurred and has been attributed, at least in part, to a "Westernization" of lifestyle. Recently, it has been observed in several countries that the mortality associated with breast cancer is dropping. This may be due to changes in the biology of tumors (e.g., a greater proportion of estrogen-receptor-positive tumors), earlier presentation as a result of screening and education of the public, and improvements in treatment. About one third to one half of patients with breast cancer benefit from these improvements, so -- with such a common disease -- modern management that incorporates these improvements can affect the lives of many women. The goal of Roses's Breast Cancer is to present current issues in the diagnosis and managemen
The new edition of the Manual of Exercise Testing is the perfect companion for the exercise testing laboratory. Filled with practical examples and diagnostic clues, this handy manual covers exercise testing for the main cardiovascular problems faced today. Testing and interpretation are extensively covered in this manual. There is a new section on exercise physiology to provide essential science background.
This book addresses the role of mechanical factors in the development, adaptation, maintenance, aging, and repair of skeletal tissues such as bones, cartilage, tendons, ligaments, and muscles. The authors show how the normal develoment of skeletal tissues is influenced by mechanical stimulation beginning in the embryo and continuing throughout life into old age. They also show how degenerative disorders such as arthritis and osteoporosis are regulated by the same mechanical processes that influence development and growth. Skeletal Function and Form bridges important gaps among disciplines and will appeal to a wide audience of bioengineers, zoologists, anthropologists, paleontologists, and orthopedists.
The majority of young people in the American juvenile justice system have diagnosable mental illnesses，including substance abuse，mental retardation and learning disorders。However，these often remain undetected and untreated。 In this book，a team of experts examines the prevalence of mental disorders in this population and describes the means of screening for，diagnosing，and treating them effectively in a developmentally appropriate，culturally sensitive manner。They also examine psychopharmacologic and psychotherapeutic approaches；innovative alternatives to detention；the true costs of detaining youth；vulnerability to self-incrimination；and the alarming trend of minority confinement。Their comprehensive coverage includes discussion of ethical dilemmas and the need for preventive strategies and integrated approaches involving judicial，law enforcement， educational，and mental health professionals。 This book will be of interest to both mental health and juvenile justice professional
Searching for alternative treatments for pain? This friendly, do-it-yourself guide introduces you to the basics and benefits of acupressure and reflexology, showing you step by step how to nurture your emotional and physical well-being and that of someone else. You'll see how to target specific body parts to address your ailments and improve your emotional as well as your physical well-being. Understand basic healing principles Relieve your specific aches and pains Boost your immune system Address age-related ailments Find professional help
Part of the nursing Secrets Series , Emergency Nursing Secrets, 2nd Edition is written in a question-and-answer format, providing concise information in an easy-to-use layout. This comprehensive resource is designed for both new and experienced emergency nurses and provides a wealth of helpful "pearls" or "secrets" of practice. Logically organized for quick access to key information, this book is divided into four main sections: Practice Topics, Chief Complaints, Trauma Care, and Special Populations. Written by experts in the field of emergency nursing. The 100 Top Secrets are listed in the front of book for quick reference. Key Points boxes in each chapter outline important information for at-a-glance access. Internet Resources boxes offer readers additional information via the Internet. Four new chapters on Resuscitation Issues, Endocrine Emergencies, Hematologic Emergencies, and Drug and Alcohol Impaired Patients Expanded coverage of bioterrorism and weapons of mass destruction i
This is not a book on how to make a diagnosis, but rather starts from the point of diagnosis and covers all the main neurological conditions as such as stroke, Parkinson's disease, epilepsy and migraine well as some of the rarer conditions such as Wilson's disease showing which treatments are evidence-based but also describing those which at present need more trials. Each condition is described in the following way: definition, cause, frequency, and prognosis. Written by expert contributors, this book describes the treatment that neurologists are responsible for, indicates when to refer, shows complications of treatment, as well as drug interactions. ·A quick-reference pocket guide ·Evidence-based treatment described ·Adverse effects of treatment mentioned along with their likelihood ·Advice given on when to refer ·Drug treatments interactions, costs, dosages are covered extensively
This timely new atlas of emergency radiology offers practical guidance to help the reader make efficient, accurate clinical decisions. The highly visual format provides a unique look at challenging cases which involve radiographic interpretation of plain films of multiple body systems. More than 400 superb illustrations guide the reader through cardiothoracic, spinal, and abdominal imaging, as well as radiography of the skull and face, extremities, bony lesions, and more. State Univ. of New York, Syracuse. Practical atlas of radiology for physicians and residents. Does not focus on technical aspects of radiographic imaging, rather, on difficult cases involving radiologic interpretation of plain films of multiple body systems. Includes abundant, high-quality halftone illustrations and succinct commentary. DNLM: Emergencies--Atlases.
The pocket atlas is an excellent reference work that presents pathologic findings in all clinically relevant fields, using high-quality photographs and concise, well structured explanatory texts. Images include color photos and micrographs. Electron microscopic images are included where necessary. Clear schematic drawings illustrate procedures such as the course of infections, etc. Text boxes on clinical and morphological aspects, on complications, and with easy-to-remember mnemonic summaries are set off in color.
This title is directed primarily towards health care professionals outside of the United States. This book aims to fill a gap with an in-depth exploration of nursing ethics content from the western philosophical tradition and some of the methods used in teaching this content. It addresses cross-cultural issues in using specific ethics content. It also reveals the poverty of the present dualism model in nursing ethics and replace this with a more complex and more useful model that invites debate. Its scope is both wide and deep but that is needed to enrich the basis for teaching nursing ethics. Outlines and critiques all current ethical theories and considers their application to nursing practice Explores ethical issues in numerous cultures Includes case studies drawn from a range of countries Written by leading nurse educators and philosophers in the field.
The health care industry differs from most other industries in that medical pricing is primarily administered by the government and private insurers and in that it uses several types of contracts. Providers may receive a fixed sum for all necessary services within a given period of time, for the necessary services to treat a given condition, or for each specific service. The industry is changing dramatically, offering many natural experiments to aid understanding of the economics of pricing for health care. In Pricing the Priceless, Joseph Newhouse explains the different pricing systems and how they affect resource allocation and efficiency, focusing on the efficiency of pricing. He also discusses larger issues of equity, fair distribution of burden, and social justice. Although most of the examples are American-based, the same issues arise in all medical care financing and delivery systems, and the theories and models are general enough to apply to many institutional contexts. The topics include Medica
This title is directed primarily towards health care professionals outside of the United States. It provides a concise, humorous, and carefully written and illustrated guide to paediatric clinical skills, including the skill of history taking from the child at various ages and from the parents, as well as examination of the body systems. The style is appealing and easy to read, and contains advice and tips based on the authors' years of experience and study. Divided into short, manageable chapters Useful illustrations and tables All terms are clearly defined Links examination technique to clinical examples Includes terms and mnemonics section and clinical checklist New illustrations and page design New material on the acutely ill child and the terrified toddler New information on syndrome recognition
Kessler, bestselling author of Running Money, made his fortune speculating on Silicon Valley. Now he turns his nose for new technology to medicine. Will the same advances that revolutionized computers ripple through hospitals, changing how health care works? Kessler interviews doctors, technicians, radiologists and the businessmen behind technology in medicine. Advances in radiology—which encompasses all the ways we peek inside our bodies, from X-rays to MRIs—are beginning to make our hospitals look like Star Trek. New scanners can provide a high-resolution, three-dimensional image of the heart and allow doctors to spot blockages. Computer-aided diagnostic software is slowly replacing radiologists in looking for cancer in mammograms. But HMOs, lawsuits and patients' desire for personal care may prevent these new techniques from ever being used. As Kessler asks, "What if the future was here with no one to pay for it?" Kessler has a raconteur's ability to entertain, and his outsider's view of medicine is fa
Applied Radiological Anatomy for Medical Students is the definitive atlas of human anatomy, utilizing the complete range of imaging modalities to describe normal anatomy and radiological findings. Initial chapters describe all imaging techniques and introduce the principles of image interpretation. These are followed by comprehensive sections on each anatomical region. Hundreds of high-quality radiographs, MRI, CT and ultrasound images are included, complemented by concise, focussed text. Many images are accompanied by detailed, fully labelled line illustrations to aid interpretation. Written by leading experts and experienced teachers in imaging and anatomy, Applied Radiological Anatomy for Medical Students is an invaluable resource for all students s of anatomy and radiology.
Conversations between AIDS counselors and their clients bring delicate and potentially threatening issues into play. In this study Anssi Per kyl applies the principles of conversation analysis to his exploration of AIDS counseling, using data from video-recorded counseling sessions in a London teaching hospital, and analyzes the design and placement of questions in these situations. His conclusions provide a timely and illuminating insight into the management of a sensitive topic through various techniques of indirectness.
The most important core skills for medical students to master are history taking and clinical examination. This extensively revised, eighth edition has been written with the philosophy that the acquisition of clinical skills is most effectively undertaken at the bedside. This pocketbook should be used as a companion, to be taken onto the wards and into consulting rooms where the information is most needed. The book begins with a system of history taking followed by a new chapter on the analysis of key symptoms. The remaining chapters cover physical examination of each of the major systems. Each stage of the examination starts with a detailed, step-by-step de*ion of the examination method complemented by relevant illustrations, diagrams and tables on the facing page. This book is intended primarily for use at the outset of clinical training; once students have achieved proficiency in the basic skills of interviewing and examining, the book should also prove useful for revisio * An invaluable start
